What is Profhilo? Profhilo is an award-winning bio-remodelling injectable formulated with 64mg of ultra-pure Hyaluronic Acid. Administered personally by GMC-registered Dr. Andy Whelan at Beauty Naturalé in Wakefield, it stimulates four types of collagen and elastin to firm, lift, and intensely hydrate sagging or crepey skin without altering your natural facial features.
Unlike traditional dermal fillers that add structural volume or change the contours of your face, Profhilo is classified as an injectable bio-remodeller. Developed using patented NAHYCO® thermal technology, it bonds high-molecular-weight and low-molecular-weight hyaluronic acid without chemical cross-linking agents (BDDE-free). Once injected into the superficial subcutaneous layer, Profhilo disperses smoothly beneath the skin, creating an internal moisture reservoir that actively triggers neocollagenesis (the production of new collagen) and elastogenesis over 8 to 12 weeks.
Profhilo is administered using the standardized BAP (Bio Aesthetic Points) protocol. Dr. Andy Whelan precisely maps 5 anatomically safe injection points on each side of the face:
This precision technique minimizes discomfort, avoids major facial blood vessels and nerves, and requires zero downtime.
Profhilo is clinically proven to treat thin, delicate areas prone to premature ageing:
| Treatment | Primary Mechanism | Best For | Typical Longevity |
|---|---|---|---|
| Profhilo | High-concentration Hyaluronic Acid bio-remodelling | Skin laxity, dullness, fine lines & crepey neck | 6 – 9 months |
| Polynucleotides | Salmon DNA fragments & cellular repair | Dark under-eye circles, deep tissue regeneration & rosacea | 6 – 12 months |
| Dermal Fillers | Cross-linked HA gel structural volume | Cheek enhancement, lip definition, jawline sculpting | 9 – 18 months |
At Beauty Naturalé, your safety is directed by Dr. Andy Whelan (MBChB, GMC Registered). In a market where non-medical injectors perform complex facial procedures without clinical governance, receiving your treatment from a qualified medical doctor ensures:
Profhilo requires a primary course of 2 treatments spaced 4 weeks apart for maximum collagen stimulation, followed by a single maintenance session every 6 months.
Does Profhilo hurt?
Discomfort is minimal. Dr. Whelan uses ultra-fine needles, and each injection takes only a few seconds. A topical numbing cream is available for sensitive patients.
How quickly will I see results?
You may notice an immediate hydration boost within 7–10 days. The true bio-remodelling lifting effect develops after your second session at weeks 4–8, as new collagen and elastin mature.
What is the downtime after Profhilo?
Downtime is practically zero. Small raised bumps resembling bee stings appear at the 5 injection sites and typically flatten within 6 to 24 hours as the hyaluronic acid disperses under the skin.
Can I combine Profhilo with Botox or Fillers?
Yes. Many patients in Wakefield pair Botox (to relax dynamic upper face wrinkles) with Profhilo (for overall mid-face and lower-face skin tightening and hydration). Treatments can be staged during your consultation.
Medical Disclaimer: Beauty Naturalé is a doctor-led clinic specializing in non-surgical aesthetics. All procedures, including Botox (Botulinum Toxin Type A) and Dermal Fillers, are medical treatments requiring a face-to-face consultation with a qualified prescriber to assess suitability. Results may vary. | Wakefield Aesthetics
📋 Last Medically Reviewed: October 2026 by a qualified medical professional | Our Clinical Standards